

F.A.Qs
Shedding Some Light on Your Questions
Found below are some frequently asked questions about Alliance Healthcare the services we offer and some general questions pertaining to our field. If you have any questions about any of the following information or anything pertaining to us at Alliance, please don’t hesitate to come in and ask. Our professionals are always on hand and would be happy to field any inquiries you have about leading a happier, healthier life.
How can I avoid the aches and pains of gardening?
The sun is shinning, the robins are out, and your garden is calling for your attention. Many people love to garden but dread the aches and pains that go along with it. There are ways in which one can enjoy the rewards of gardening while decreasing the risk of pain and damage to your body. Gardening activities contain many of the risk factors, such as repetitive twisting and stress, associated with Cumulative Trauma Disorders, i.e. carpal tunnel syndrome and tendonitis as a result of repeated micro-traumas to the soft tissues of the body. It is very important to remember that the most important gardening tool we have is our body. Proper body positioning, well designed gloves and tools and frequent rest breaks are the key to being a healthy gardener.
Use Proper Body positioning to minimize muscle fatigue and soreness
Back:
Bend at the knees and hips to lift and hold objects and keep one arm under the object while carrying. Use an erect body posture when working at ground level or when using long-handled gardening tools such as hoes, spades and rakes. With existing back problems, consider raised beds to minimize bending and lifting.
Shoulders
Work below shoulder level whenever possible. When it is necessary to work above shoulder level, perform the task for five minutes or less; then take a break or perform another activity before continuing. It is very important to use both arms whenever possible.
Elbows/Forearms:
Keep the elbows partially bent while gardening, especially when doing activities requiring elbow strength. Avoid twisting the forearms back and forth on a repetitive basis, for example pulling weeds by twisting the forearm palm up and then palm down. Whenever possible, work with the forearms in a neutral position, for example thumbs up.
Wrists/Hands:
Work with the wrists in a neutral position by avoiding the extremes of motion, up, down and sideways. Grip strength is at its maximum when the wrist is in a neutral position. Hold objects with a light grasp or pinch, avoiding a tight, sustained grip.
Tools:
Shorter tool handles provide greater leverage control and longer hand tools provide greater power and are best for jobs which require full body motion. Many tools are made with finger grips molded into the handle, to provide better slip resistance. People with larger hands will find that their fingers overlap the ridges, causing pain, soreness, and calluses. Those with smaller hands will have to spread their fingers to match the grooves. (Picture 2-1) Handles should be cylindrical in shape, contoured, not straight to provide equal pressure along the entire arch of the palm, made of compressed rubber to minimize friction, 1.25” x 1.75” in diameter and a minimum of 5” long.
Gloves:
Gloves protect the hands from chemicals, sharp items and blisters, but they do decrease overall hand coordination and power grip. Gloves should be form-fitting without being restrictive.
Please remember:
Take a few minutes to stretch before, during, and after, to help minimize muscle soreness. Be sure to drink plenty of water, and change your gardening tasks frequently (at least every 30 minutes). Make sure you allow your physical activity level to act as your guide for how long you can garden. If you are physically active 1 hour a day, you should be able to garden an hour a day. Finally, remember a healthy spine will allow your body to function optimally! See your chiropractor today for an assessment so your body and garden can be in perfect shape all summer long!
Heart Facts

What don’t I know about my heart?
- The heart beats 100,000 times a day, approximately forty million times a year - nearly three billion pulsations in seventy years. It pumps over 100 gallons of blood per hour through a vascular
system about sixty thousand miles in length (over two times the circumference of the earth).
- The heart's electromagnetic field is approximately 5000 times greater in strength than the field produced by the brain.
- The heart has its own brain with over 40,000 neurons which include every type of neuron found in the brain.
- The heart communicates with the brain in at least four different ways; neurological, chemical, blood pressure wave, and electromagnetic. The heart sends more signals to the brain, than the brain does to the heart.
- The heart starts beating in the unborn fetus before the brain has been formed.
- The rhythmic beating patterns of the heart directly affect the electrical activity of the higher brain centers causing inhibition or facilitation of our thinking process.
For more information on HeartMath® please book a free consultation with me at your earliest convenience—You Can Learn It Too!
This information is from the book The HeartMath Solution by Doc Children and Howard Martin.
Vitamin D & Multiple Sclerosis

The Protective Effects of Vitamin D & Multiple Sclerosis
For almost half a century scientists began to recognize that there were higher rates of chronic disease for those peoples who lived outside of the tropics. Researchers concluded that the higher intake of vitamin D had some protective qualities.
In the January issue in the journal Neurology researchers at Harvard School of Public Health reported from a two-phase Nurses’ Health Study. The use of multi-vitamins and monitoring of diets of more than 190, 000 nurses were tracked over a twenty year period.
A total of 173 cases of MS were reported. Two significant results were as follows:
- Women, who had the highest intake of supplementary vitamin D, had 40% reduced risk of developing MS compared with the group that took no supplements at all.
- Risk was not reduced by women who had vitamin D from food sources but took no supplements.
The lead author of the study, Dr. Kassandra Munger, told BBC news, “It’s exciting to think something as simple as taking a multi-vitamin could reduce your risk of developing MS.”

In addition to prevention, vitamin D may also be an essential element in the treatment of MS after the disease has been diagnosed. In one study patients took 5000 iu Vit. D, 1000mg Calcium and 600mg Magnesium. Subjects showed a clear decline in the rate of disease activity and symptoms after supplementation began.
Multiple sclerosis is an autoimmune disease and research shows that people who live further away from the equator are thought to be at a higher risk for other autoimmune diseases as well.
In the November 2003 issue of Nutrition and Healing, Dr. Jonathan Wright, MD, discussed the importance of supplementation as the suns’ rays do not penetrate as deeply in the winter months. The estimated cutoff area is about 35 degrees. In other words if you drew a line from Los Angeles to North Carolina everyone north of that line would benefit from Vitamin D supplementation during the winter months.
Dr.Wright recommends for those who do not get enough winter sun a supplement of 2000-4000ui on a daily basis. Recent research suggests upward limits of 10,000ui per day are within safe dosages.
Sources: Vitamin intake and Incidence of MS – Neurology vol. 62, Nutrition & Healing, Jonathan Wright MD, HIS Newsletter
Vaccines & My Children

The Top 7 Questions a Parent Needs to Ask When Contemplating a Vaccine for their Child
More recent research has come to light that shows a correlation between vaccines and certain syndromes like autism etc. While I do not personally wish to make a decision for my patients I do think that it is critical that parents well informed in order to make sound health choices for their children. Consider some of the following information when making your decisions.
The pharmaceutical industry with its strong legislative and marketing arms have led the public to believe three myths. One that vaccines are safe, two, that such vaccines are totally effective, and third, that every child has to have them.
First vaccines are not safe. The U.S. government has paid out over a billion dollars to compensate families who have children that have died or become injured from a vaccine. Also it is widely accepted that only a fraction of the true number of vaccine injuries and deaths are reported or compensated.
Second, vaccines are not totally effective because there are many documented cases of diseases or outbreaks in the vaccinated populations that were supposed to be protected.
Third, not every child has to have vaccinations. In most states and provinces, there are up to three exemption from vaccination. You can either use a religious, medical or philosophical exemption to avoid vaccination. I know that here in Ontario we had to have exemption forms notarized and filed with the province.
Childhood vaccination is not primarily a chiropractic issue but a freedom of choice issue. A parent needs to be fully informed and have a choice if their child is being subjected to a medical procedure that carries a risk for serious injury, disability or death. Vaccinations do contain toxins and carcinogens that are used to manufacture the vaccines. If you are interested in preventing Vertebral Subluxation in children, we need to look at the role of vaccines in producing a chemical cause of vertebral subluxation in children.
Many people would be surprised to know that U.S. congressional hearings have shown that up to seventy percent of the individuals that make up the FDA advisory committees that approve new vaccines to bring the market have conflicts of interest and financial ties to the vaccine manufacturers. Also researches that test the safety of certain vaccines before approval check the safety of an intended vaccine compared to another experimental vaccine instead of a placebo. Those of you familiar with proper research protocol know that this method is flawed.
The following top seven list is a good starting place to start a parent's journey on getting informed and making a decision that is best for their child.
- ASK "Is my child sick right now"
- ASK "Has my child had bad reactions to a vaccine before?"
- DID YOU CHECK your family medical history for records of vaccine reactions, convulsions, neurological disorders, severe allergies or immune system problems?
- DID YOU GET full information on vaccine side-effects and how to identify a potentially severe reaction?
- DO YOU UNDERSTAND how to report adverse reactions?
- DO YOU KNOW the vaccine manufacturer's name and lot number?
- DID YOU VISIT the National Vaccine Information Center (NVIC) website (www.909shot.com) for more information and updates on vaccine research projects?
A great resource for parents to get more information or for professional and doctors to purchase books and newsletters or get advice and support is the National Vaccine Information Center (NVIC) Barbara Loe Fisher and Kathy Williams developed this top seven list cofounders of the NVIC.
What is Fibromyalgia?

Fibromyalgia, is a mysterious syndrome that is taking an increasing toll on our population. In some instances it is very similar to that of Chronic Fatigue Syndrome. Fibromyalgia is often associated with widespread pain that is often incapacitating and usually affects women in the 25-60 demographic. Fibromyalgia literally means pain in the muscular and connective tissues.
The cause of FMS is unknown and affects over 6 million North Americans. For many years the identification of fibro was very perplexing, because no blood work or other lab tests could show any conclusive evidence. Subsequent studies have shown a common thread of pain patterns and associated symptoms. Pain or point tenderness in the areas of head, neck, shoulders, upper back, elbows, ribs, buttocks, knees and legs is often associated with the syndrome. In addition to pain symptoms there is also sleep pattern disturbance, TMJ syndrome, irritable bowel, chronic headaches, dizziness, sensitivity syndrome, numbness in the extremities, and the list goes on.
With all these symptoms how does one make a diagnosis or evaluation. Usually lab work is negative and actual identification is difficult therefore many victims are anxious and perhaps even depressed because of the lack of concrete evidence. Most patients will have 11 of the 18 points of tenderness and widespread pain in all four quadrants for a duration of at least three months.
Causes of FMS are still very much unknown however there appears to be some common clinical histories. Many patients have been involved in an even a minor motor vehicle accident (untreated), emotional or physical stress, hormone imbalance, nervous system interference, or nutritional component.
Current treatment regimens that include medication and drugs are not all that successful. It is my opinion that a multi disciplinary approach to the syndrome is key to its management. First off everyone should be evaluated to establish if they have nerve interference called vertebral subluxation. Chiropractic is exclusive in its mission to detect and remove subluxations. In addition to chiropractic, nutritional balance and support is showing very promising results.
Supplements like MSM assist in managing pain. Exercise geared at stretching muscles and improving cardiovascular is helpful. Relaxation techniques and massage therapy is helpful. Our approach also includes physical therapy, and evaluation of the feet by our foot specialist to ensure a proper foundation to stand on.
This multidisciplinary approach has provided a solution to a very difficult situation. If you know someone who is suffering from FMS call today.
Whiplash

Chiropractic "Only Proven Effective Treatment" for Chronic Whiplash
Study Says 74% of Chronic Whiplash Patients Improved with Chiropractic. A new study published in the Journal of Orthopedic Medicine not only points out the superiority of chiropractic care for chronic whiplash patients, but also examines which chronic whiplash patients respond best to chiropractic care. The authors begin the paper by explaining that:
"Conventional treatment, of patients with whiplash symptoms is disappointing”. A retrospective study by Woodward et al., demonstrated that chiropractic treatment benefited 26 of 28 patients suffering from chronic whiplash syndrome.
The question was not whether chiropractic was beneficial for acute whiplash patients, but to determine "which patients with chronic whiplash will benefit from chiropractic treatment." The authors interviewed "100 consecutive chiropractic referrals for chronic whiplash symptoms," seven of which were "lost to follow up." They were able to divide the remaining 93 patients into three symptom groups:
Group 1: patients with "neck pain radiating in a 'coat hanger' distribution, associated with restricted range of neck movement but with no neurological deficit";
Group 2: patients with "neurological symptoms, signs or both in association with neck pain and a restricted range of neck movement";
Group 3: patients who described "severe neck pain but all of whom has a full range of motion and no neurological symptoms or signs distributed over specific myotomes or dermatomes." These patients also "described an unusual complex of symptoms," including "blackouts, visual disturbances, nausea, and vomiting and chest pain, along with a nondermatomal distribution of pain."
The patients underwent an average of 19.3 adjustments over the course of 4.1 months (mean). The patients were then surveyed and their improvement reported as follows:
Group 1
24% - Asymptomatic
24% - Improved by Two Symptom Grades
24% - Improved by One Symptom Grade
28% - No Improvement
Group 2
38% - Asymptomatic
43% - Improved by Two Symptom Grades
13% - Improved by One Symptom Grade
6% - No Improvement
Group 3
0% - Asymptomatic
9% - Improved by Two Symptom Grades
18%- Improved by One Symptom Grade
64%-No Improvement
9% - Got Worse
In their discussion, the authors made these observations:
"Woodward, et al.,2 found improvement in chronic symptoms in 26 of 28 patients
(93%) following chiropractic treatment. Our results confirm the efficacy of chiropractic, with 69 of our 93 patients (74%) improving following treatment.
"Our study suggests that such a group of nonresponders does exist, represented by group 3. The defining characteristics of patients in this group were the full range of neck movement in association with neck pain, bizarre symptoms, female sex and ongoing litigation. The mean age of the group at 29.5 (16-43) was lower than that of the other two groups (mean 36.8, range 18-65).
"The results from this study provide further evidence that chiropractic is an effective treatment for chronic whiplash symptoms. However, our identification of a group of patients who fail to respond to such treatment, highlights the need for a careful history and physical examination before commencing treatment."
References
1.Khan S, Cook J, Gargan M, Bannister G. A symptomatic classification of whiplash injury and the implications for treatment. Journal of Orthopaedic Medicine 1999;21(1):22-25.
2.Woodward MN, Cook JCH, Gargan MF, Bannister GC. Chiropractic treatment of chronic whiplash injuries. Injury 1996;27:643-645.
Flu Shot
Flu Shot Controversy
Flu shot controversy!!! Over the last few years there have been continuing arguments over the efficacy of the flu shot. Right here in Ontario many of the paramedics refused to entertain mandatory flu shots. I think that people have a right to make that decision on their own...specifically what goes into their bodies. Let's not lose sight of the fact that we do not know what the long-term implications of this type of treatment are. Read the following and include this type of information in your decision making process.
Knowledge and information allows you to be empowered to make correct health care choices.
Why I Never Get Flu Shots - by Chet Day
Every year about this time, quite a few people write me and ask, "My Doctor tells me to get my annual flu shot. Should I do it?" Well, I don't diagnose or prescribe, and what you do with your body remains entirely up to you and your doctor (if you still go to a doctor), but I'll gladly tell you what I do regarding flu shots....... I avoid them like the plague.
In fact, at age 52, I've never had a flu shot, and it would take a Marine nurse and at least four burly wrestlers the size of Jessie Ventura to hold me down and give me one. Perhaps you already sense I have strong feelings about flu shots? These feelings stem from personal opinion, reading, and dramatic personal experience. First off, I don't think toxic chemicals and virus strains grown on living tissue belong in the human body, even when they're packaged in sterile glass vials.
Since my family and I don't rely on doctors anymore, I don't have access to an insert that reveals the composition of this year's flu vaccine, but I did find some general information at the Concerned Parents for Vaccine Safety web site, where I learned about some of the ingredients used to make vaccines.
- Do you want any of the following vaccine constituents in YOUR bloodstream?
- Ethylene glycol (antifreeze)
- Phenol, also known as carbolic acid (this is used as a disinfectant, (dye)
- Formaldehyde, a known cancer-causing agent
- Aluminum, which is associated with Alzheimer's disease and seizures and also cancer producing in laboratory mice (it is used as an additive to
promote antibody response) - Thimerosal (a mercury disinfectant/preservative) can result in brain
injury and autoimmune disease - Neomycin and Streptomycin (used as antibiotics) have caused allergic
reaction in some people.
Vaccines are also grown and strained through animal or human tissue like monkey kidney tissue, chicken embryo, embryonic guinea pig cells, calf serum, and human diploid cells (the dissected organs of aborted human fetuses as in the case of rubella, hepatitis A, and chickenpox vaccines).
Well, I refuse to put all of the above in my body, and I hope when your doctor starts telling you it's time for your annual flu shot that you'll require him to defend the annual injection. You or your insurance company's probably paying eighty bucks for a visit, so get your money's worth. Have your doctor read you the insert that comes with the vaccine. Then have him/her explain why it makes sense to inject toxic chemicals into the human body and how such substances can aid the delicate immune system.
Chances are he/she will fall back on questionable statistical and demographic explanations that the medical establishment has used for decades to justify immunization. Try to engage your doctor in a non-confrontational discussion because this is an opportunity for him/her to actually give some serious thought to what he/she is injecting into bodies of patients day after day after day. Many traditional doctors who haven't studied diet and lifestyle aren't going to change unless we help to educate them to what drugs and vaccines may really be doing long-term to people. Okay, to speak from personal experience for a moment, let's look over our shoulders to 1990, a time period before the Day family turned to natural methods of building health. In February of 1990, right after my wife's major cancer surgery in January, her doctor recommended a flu shot. Almost immediately after the injection, my wife started feeling ill.
Overnight she came down with the worst case of flu she'd ever had. She went to bed and literally didn't get up again for more than a few hours at a time for years afterwards. Only now, almost a decade later, is she finally regaining full health and energy. I don't have space or enough heart yet to tell my wife's entire story, though I'll do it one of these days, you can read an article written by another CFIDS sufferer, an article that shows the cause and effect connection between flu vaccines and terrible immune disorders.
Okay, I'm a realist so if was still thinking traditionally, part of me would almost buy into the typical rationale for flu vaccines, that so many people are spared the annual flu and only a few die or have their lives ruined after being injected. I'd buy into that if I were convinced that injecting a filthy substance into the body actually made sense. Unfortunately, once I stopped buying into the big medical lies about their drug, cut, and burn system, I started questioning all of it. And when one digs into the vaccine history (check out the Swine Flu vaccine if you want a real horror story) and scientific research (especially in Europe), it quickly becomes apparent that nobody really knows what these toxic stews of chemicals and microorganisms do in the human body. Well, readers and a few medical professionals have called me a simple-minded dolt on more than one occasion, but since 1993 I've approached the yearly flu shot hype with the understanding that if I eat
and live properly, I won't have to worry about catching the flu.
The flu vaccine I use -- eating and living as close to nature as I can
-- actually works.
Not only that, but it doesn't cost a dime, and nobody's going to have his/her life ruined because of a "bad batch" of vaccine that triggers some mysterious autoimmune disease that lays a person out of commission for years. But let's say you don't want to eat and live close to nature. Okay, I can understand that, but my next question would be "Which is better? Some rest time with the flu or having toxic chemicals injected into your bloodstream?" I mean, seriously, before I got healthy I almost looked forward to a yearly bout with influenza because it meant I could go to bed and get some rest instead of working practically every waking moment of my life.
I might add that I haven't missed more than two consecutive days of work from an illness for almost five years, so a non-vaccine approach does work for me. This non-drug approach has resulted in a level of health that continually amazes me, especially when I see other men and women my age who are miserable and without energy. Men and women who spend all too much of their time drifting from doctor to doctor in endless pursuit of solutions that don't get to the cause of their problems -- diet and life style.
Visit Chet's Health and Beyond (www.chetday.com) which has lots of interesting and useful information.
I personally agree with the flavour of this article. Health is based upon five principles...namely a properly functioning nervous system , moderate exercise, proper nutrition, rest , and a positive mental outlook...naturally one has to avoid toxins as much as possible and realize that health is from inside out...not from a bottle.
Dr. Huggins
Chiropractic and children

Healthier Children Through Chiropractic
Chiropractic care for my child? Why? His back doesn't bother him." How often chiropractors have encountered parents who appreciate the importance of regular checkups for their child's teeth, hearing, eyes and ears but draw a blank when it comes to a spinal checkup. In fact, a spinal check up could be one of the most important checkups your child will ever have. Your child's spine is their lifeline because running through it is the spinal cord, containing billions of nerve fibers that send messages and energy from the brain to every part of their body. If there is blockage of any of the nerves along the spinal cord, any nerve damage at all, then a state of " dis-ease" will develop. Dis-ease means dis-harmony in the body that will cause generalized weakening of your child's body, lowered resistance to disease, and consequent body malfunction and sickness.
Blockages of nerves in the spinal column are usually caused by tiny fixations and misalignments of the spinal vertebrae that are called vertebral subluxations. Only chiropractors are trained to detect and correct subluxations, much like only a dentist finds cavities. Subluxations can be cause by the birth process, the very physical childhood activities of running and jumping, falls and accidents. Because your children (and you) may have spinal subluxations and not know it, all children need periodic spinal check ups. There are however certain warning signs indicating that the spinal column may be out of alignment. One hip or shoulder is higher than the other, hyperactivity and can't sit still, frequent falling, a foot turned in or out (foot flare), neck tilt, one leg shorter than the other, chronic fatigue, "noisy bones" or joint aches, and skin conditions. Some other indicators are increased allergies, colds and flu, asthma and ear infections. A recent study of 332 children showed that chronic ear infection sufferers under chiropractic care had no more infections in 80% of the cases (JCCP, Vol.2, No.2 1997).
The Chiropractic Approach - By releasing stress on the nervous system with very gentle and safe chiropractic adjustments, the body will work more effectively and be able to express better health. The nervous system controls EVERY function of the body (Gray's Anatomy) and thus the nervous system when not interfered with by subluxations can enable the body to heal itself and be healthy. No matter what health concerns you or your children may have, you can benefit from a healthy spine. Spinal health can be as important for your overall healing as proper nutrition. Are you and your family carrying vertebral subluxations in your spines? A spinal checkup can tell. Among the many things contributing to your health: the quality of the air, food and water you take in, how you handle stress, your inherited weaknesses, strengths and activity levels - a healthy spine is absolutely essential. In some people and children it is a major factor and can make the difference between a life of health, strength and vitality or a life of disease, weakness and disability. More and more families are finding that chiropractic care for their child makes a big difference in their health. Every day we see children in our office getting healthier as they receive adjustments, because their parents who saw benefits from chiropractic care for themselves wanted their children to have the same. One of the comments that we hear over and over again is "My child doesn't seem to get sick as often since getting adjusted."
Colds in day care

Colds in Day Care Give Immunity
Later On
Colds frequently passed among toddlers attending day care provide a measure of immunity by the time the children reach school age, offering worried parents some comfort, researchers said on Thursday. Two-year-olds enrolled in day care centers attended by six or more children caught twice as many colds as children of that age cared for at home, according to a study of 1,246 children in Tucson, Arizona.
But between the ages of 6 and 11, those who had attended day care suffered fewer colds than their counterparts cared for at home during their preschool years. By the age of 13, all the children were at the same risk of developing colds.
"Regardless of whether children acquire that immunity in preschool or primary school, they seem to have similar levels of protection by 13 years of age," Thomas Ball of Arizona College of Medicine wrote in the Archives of Pediatric Adolescent Medicine, a journal published by the American Medical Association.
Upper respiratory tract infections account for 75 percent of illnesses suffered by U.S. infants and about half of all illnesses, the report said. The common cold is responsible for about 23 million days of missed school and 25 million missed days of work in the United States.
In 1995, 65 percent of 4-year-olds were enrolled in day care or nursery school.
"Clinicians may continue to reassure parents of children in day care that their child's plight with minor respiratory tract illnesses is not in vain," Ball wrote.
Dr. Huggins Comments: This study underscores the position that I have held for years in that your immune system goes through a learning curve experience. In years past measles, mumps, chicken pox etc were always referred to as usual childhood diseases. The intelligence of the body takes those experiences and learns to fight off more serious issues later on in life. It has been suggested that measles is particularly important for women and the health of their reproductive organs. The innate intelligence has a tremendous ability to adapt to a hostile environment as long as there is no interference. So the next time your child has a runny nose or moderate fever understand that the body is "doing its thing" and learning how to face future challenges.
Aspirin facts

Health Myths May cause more Harm - Know the Facts
How often have you heard that an aspirin a day is good for preventing heart disease? When the actual study is reviewed we find this out not to be the case. In whose best interest is this idea promoted anyway? There is a serious risk associated with a daily dose of aspirin so make sure that you understand the facts and ask the right questions. Knowledge is empowerment for you and your family.
Aspirin Not Recommended for Heart Disease Anymore
By Dr. John G F Cleland
Despite the vast size of these meta-analyses, the evidence in support of aspirin preventing atherosclerotic events is still inconclusive. The third meta-analysis from the Antithrombotic Trialists' Collaboration contains data on over 100 000 patients at high risk of atherosclerotic events, representing more than 250 000 patient years of follow up.1 This meta-analysis and its predecessors form the major argument for the current widespread fashion of prescribing aspirin to such patients. 2 3 It is an enormous body of research and the collaboration is to be congratulated for having gathered so much data. However, quality as well as quantity matters. And the quality is such that the results can only be inconclusive.
Summary Points:
- The series of meta-analyses on the antiplatelet activity of aspirin overvalues aspirin's effectiveness and safety
- All the large long-term trials of aspirin after myocardial infarction show no effect on mortality
- Aspirin may change the way vascular events present rather than prevent them
- This may lead to a "cosmetic" reduction in non-fatal events and an increase in sudden death
- Data on the safety and cost-benefit of aspirin are inadequate
- Advocating the use of aspirin for preventing atherosclerotic events diverts attention from other, more effective, drugs
Trials Do Not Show That Aspirin Saves Lives
Meta-analysis is increasingly viewed either as a way of verifying that the outcome of an individual trial is consistent with the rest of the data or as a way of generating a hypothesis. However, in the absence of a definitively positive trial, many consider meta-analysis inadequate evidence for clinical decision making. The series of meta-analyses from the trialists' collaboration contains serious additional flaws.3-6 It is remarkable and probably statistically significant how seldom trials of antiplatelet agents have shown benefit on their selected primary outcome.
The choice of the primary endpoint by the Antithrombotic Trialists' Collaboration is arbitrary and suspect. Antiplatelet agents seem to be substantially more effective in reducing the incidence of non-fatal events than in reducing death. Indeed, among large long-term trials after myocardial infarction there is no evidence that aspirin saves lives.
An intervention can reduce non-fatal events in three ways: by genuinely reducing them, by concealing them, or by converting non-fatal events into fatal ones. The failure of aspirin to reduce mortality despite a reduction in non-fatal events in many studies suggests that aspirin may conceal, rather than prevent, vascular events.6 Epidemiological data suggest that 25% of non-fatal myocardial infarctions are silent. 4 5 As aspirin, even at low doses, is an analgesic and because it may provoke dyspepsia, which may create confusion about the cause of chest pain, it is not difficult to believe that aspirin could increase the proportion of silent events from 25% to 30%. This could explain all the benefits of antiplatelet agents on non-fatal myocardial in the meta-analysis. Aspirin increased the risk of sudden death in every long-term study after myocardial infarction that reported such events.
This increase was from 4.4% on placebo to 5.6% on aspirin in the persantine-aspirin reinfarction (PARIS) study; from 2.0% to 2.7% in the aspirin myocardial infarction study (AMIS); and from 2.0% to 2.4% in the persantine-aspirin reinfarction study (PARIS-II).9 This could reflect an increased risk of sudden death among concealed, and therefore untreated, events. Another possible mechanism by which aspirin may convert non-fatal events into fatal ones is by increasing the risk of hemorrhagic conversion of cerebral and myocardial infarctions. All cause mortality and, arguably, disabling stroke are the only robust markers of benefit with an antiplatelet agent. It is not clear that antiplatelet agents reduce the risk of either. Some trials that were included lost more than a quarter of their patients to follow up.10 In similar circumstances, with other agents, it has been suggested that all patients lost to follow up in the active treatment group should be considered to have died and none of those in the control arm. Such an analysis would neutralize the benefit observed in one of the few seemingly convincingly positive studies.
Bias In Interpretation
The Antithrombotic Trialists' Collaboration shows bias in the analysis and interpretation of their results. We are given scant detail on how the numbers of events credited to each trial changed between meta-analyses. 2 3 Trials were retrospectively reanalyzed, resulting in resurrection of a number of apparently dead patients and the discovery of a number of new deaths. Most interventions probably help some people some of the time and harm others some of the time. A small benefit could reflect a small overall benefit in a large population or a substantial benefit in some patients and harm in others. Aspirin could exert a short-term benefit followed by long term harm, in which case the benefits and safety of aspirin could be increased by using only a short term course of therapy.14 Aspirin may be harmful in patients with coronary disease and heart failure. 5 6 12 The evidence for an adverse interaction between aspirin and angiotensin converting enzyme inhibitors observed in the SOLVD (studies of left ventricular function) and HOPE (heart outcomes prevention evaluation) trials is also a matter for concern. 6 12 These are important issues that have not been adequtely addressed.
Neither Safe Nor Cheap
Many believe that, even if aspirin is not effective, it is safe. Aspirin does appear to be relatively safe for the patients included in clinical trials, but as these studies excluded by design patients at risk of adverse events with aspirin and tended to include younger patients with lower multiple morbidity it is likely that aspirin is not as safe as suggested. Low dose aspirin for cardiovascular prophylaxis may account for more than 30% of all major gastrointestinal hemorrhage in patients aged over 6, 4 6 15 and may also be associated with an increased risk of renal failure.
Finally, there is a widespread view that aspirin is cheap. However, when evaluating the costs of treatment the amount and type of benefit and the costs of managing adverse effects also need to be evaluated. Very few economic appraisals of aspirin have been done.
One such analysis, recently commissioned by the chief scientist's office in Scotland, suggested it may cost more than £80 000 to prevent one event with aspirin for primary prevention and more than £3000 for secondary prevention.16 These analyses have assumed that aspirin is as effective as the meta-analyses suggest, which may not be true.
A Diversion
Perhaps the greatest potential detriment of aspirin on health care, however, is that it diverts attention away from treatments that are of unequivocal benefit to many groups of patients.
The reader should not accept the conclusions of the Antithrombotic Trialists' Collaboration uncritically but rather read the original papers on which their conclusions are based.
For most people, daily aspirin does more harm than good.
Ever since drug manufacturers began promoting aspirin as a way to prevent heart attacks, millions of healthy people started swallowing the pills daily. Yet, what they didn't know about aspirin is that, not only can it have serious negative side effects, taking it isn't an effective preventive measure for everyone.
Because of this, the U.S. Preventive Services Task Force (USPSTF) has strongly recommended that clinicians discuss the benefits and risks of aspirin therapy with healthy adult patients.
The recommendation was published in a recent issue of the Annals of Internal Medicine.
The USPSTF said that the regular use of aspirin can reduce the risk of coronary heart disease (CHD) in certain people by about 28%. Only those who have never
had a heart attack but are considered at increased risk for CHD may benefit.
However, the Task Force also noted that aspirin can increase the incidence of gastrointestinal bleeding, and hemorrhagic strokes which involve bleeding in the brain.
Although the benefits of aspirin outweigh the harm for persons with an increased risk of CHD, the harm may exceed the benefits for those who are at average or
low risk for heart disease.
"Aspirin therapy is powerful, and clinicians and patients need to discuss the role of aspirin therapy in combating CHD," said John M. Eisenberg, M.D., director of the Agency for Healthcare Research and Quality (AHRQ), which sponsors the USPSTF.
SOURCE: Annals of Internal Medicine, Jan. 15, 2002.
Vaccinations and Autism
Observers are calling it a national emergency as the rate of autism among children in the US and around the world is rising by as much as 800 percent. Health authorities offer no explanations but all of the research centers around childhood vaccinations which are conducted worldwide. Autistic behavior emanates from a change in the brain's output of serotonin, which can be caused by toxic metals or toxins originating in the gastrointestinal tract.
This report reveals two major causes of autism: mercury overload from preservatives in vaccines or a sub-acute tetanus toxin infection of the gastrointestinal tract which results from the over-use of antibiotic drugs. Various nutritional measures can be taken by parents of autistic children to prevent or even reverse the symptoms of childhood autism, though most of these practices are overlooked by modern medicine. Vitamin C and chelation therapy with plant-based metal removers, use of natural antibiotics such as oil of oregano which do not result in antibiotic resistance, the consumption of tryptophan-rich foods to boost serotonin levels, the replenishment of good bacteria in the digestive tract, and other nutritional practices are recommended. Premature birth is associated with autism and the use of omega-3 fatty acids from fish or flaxseed oil may prolong gestation and reduce developmental problems among young children. Preservative-free vaccines should only be used and vaccination schedules widened to avoid excessive overload. Certain vaccines may not be necessary.
The Emergency!
Their ranks are growing. They are children who exhibit bizarre, violent behavior, children who are unable to communicate or interact socially, or who have repetitive patterns of behavior. And no one knows why. The kids are called autistic.
In the 1970s the rate of autism was about one case in 2500 children. Today it is one in 250 children. In California in the 1970s only 100-200 new cases of autism were reported annually. In 1998, new cases reported to the public-school system were 1425! In 1999 that figure jumped to 1944! In New Jersey the reported cases of autism jumped from 241 in 1991 to 1634 in 1997 (an 800% increase)! There were 4.4 cases of autism per 10,000 live births reported in California in 1980 and
20.8 cases per 10,000 live births in 1994, a 373 percent relative increase. [Journal American Medical Association 285: 1183-85, 2001]
The British Medical Journal reports that autism jumped by 700% from 1988 to 1999! [British Medical Journal 322: 460-63, 2001] In studies prior to 1988, the estimated prevalence of autism was between 4-6 cases per 10,000 children. Among 15,500 British children between the ages of 2 and 6 years of age the autism rate has risen to 17 cases per 10,000 children. When the entire spectrum of autism disorders is considered (which includes Asperger syndrome and other rare childhood degenerative disorders), the rate rises to 63 per 10,000 children. [News.telegraph.co.uk July 8, 2001] In Japan the rate of autism was 5-16 per 10,000 in the 1980s but rose to 21.1 per 10,000 in 1996, a 31-400% increase. [Japanese Journal Infectious Diseases 54: 78-79, 2001]
Whatever is causing the rise in autism, it is a worldwide factor.
Don Harkins, a reporter for the Idaho Observer, says the epidemic of autism represents a national emergency. He asks: "What sociological perils await a nation where two percent of its people are destined to be terminally institutionalized for being unable to see outside of themselves?" [Idaho Observer, June 2000]
About 3.9 million children are born in the USA annually. At the rate of 1 in 250 children, some 15,600 children born each year, 156,000 in a decade, would exhibit autistic behavior. This estimation may be very low.
There is a disparity in figures used to number the autistic population in the US. According to the Center for Mental Health Services about 125,000 Americans are affected by these disorders, striking three times as many boys as girls. According to a resolution before the US Congress, autism has robbed at least 400,000
Americans of their ability to communicate and interact with others. The government resolution said autism disorders now affects 1 in every 500 children in America, not the 1 in 250 figure cited above.
Autistic symptoms usually appear within the first three years of life. The current estimated cost of autistic care is estimated at $13 billion per year. Life time care of an autistic person averages $2 million.
What causes autism?
For many years doctors blamed parents for autistic behavior. People would bring their children to hospitals only to be treated as bad parents. Kanner formally described the disorder in 1943 but it took till the 1960s for a psychologist, Bernard Rimland, who had an autistic child, to look at autism as a brain disorder. Autism is now described as a neurological disorder which affects the areas of the brain that control social interaction and language. No cure exists in the medical texts, but that doesn't mean that these children are beyond hope.
Genetics, season of birth, and many other factors have been explored in the search for the cause of autism. Genetics accounts for less than 10 percent of cases. There are no drugs that consistently alter the course of autism. [Life Science 67: 1667-82, 2000] Nutritional therapies have been employed with some studies showing that dietary measures and magnesium/vitamin B6 supplementation are helpful in ameliorating symptoms
Mercury poisoning
The most convincing argument is that mercury poisoning, delivered to children via a mercury preservative in vaccines, is involved in the onset of autism. Many parents have observed sudden behavior changes in their children following vaccinations and believe vaccines were the cause. The diet may also contribute to the problem. Mercury from fish can be transferred from pregnant women to their developing fetus and after birth in breast milk. [Journal American Medical Assn 282: November 10, 1999]
The characteristics of mercury poisoning and autism are remarkably similar. While an infant only receives a few micrograms of mercury from vaccines, a single dose could represent as much as 353,000,000,000,000,000 mercury particles. [ARC Research, April 3, 2000]
Neal A. Halsey MD, writes in the Journal of the American Medical Association that the fetal brain is much more susceptible to mercury compounds than the adult brain.
Health authorities are likely to be less than candid about the connection between vaccinations and autism for fear of scaring the entire population away from vaccines altogether, which would give rise to a return of childhood diseases such as measles and polio that have almost been eradicated.
Thimerosal is the name of the mercury preservative in vaccines. Thimerosal has been used as a preservative in vaccines since the 1930s, but was assumed to be safe and never tested by the Food & Drug Administration. The recent rise in autism and the growth in the number of required childhood vaccinations before the age of two have paralleled each other. The list of required vaccines has risen from 8 in 1980 to 22 vaccines today, many requiring multiple injections.
But health officials defend the vaccines. The rate of autism has risen while the percentage of children undergoing vaccination has remained somewhat constant. In California, the proportion of children vaccinated with MMR (measles/mumps/rubella vaccine) before the age of 2 increased by 14% from 1980 to 1994 while the percentage of children diagnosed with autism jumped 572%! But the reasoning behind this type of defense for the vaccines is not valid. It's not the rate of vaccination but the vaccine (or mercury) load children are being delivered in a short period of time. Critics have also called attention to the fact that a child's immune system may not be ready to handle multiple vaccines all at one time. Autoimmune reactions may be responsible for autism. The bogus defense of vaccines by the scientific community is a tip off they know more than they are telling.
Another disturbing report is a survey conducted by Dr. Edward Yazbak, former medical assessor to the UK Committee on Safety of Medicines. His survey found 76 percent of mothers who had been vaccinated just before, during or after pregnancy, had one or more children with autism disorders. [Pulse Magazine, July 7, 2001] Maybe the mercury or toxic effect was striking kids via their mother. Symptoms take some time to emanate, so the delay in diagnosis might lead investigators off the track.
Boyd Haley, chemistry professor at the University of Kentucky, has said that "thimerosal is extremely toxic" and it is the "most likely suspect for causing autism."
Mercury load
A front-page story in the May 27, 2001 issue of the London Times states that "Mercury in vaccines for babies and infants could be the cause of a steep rise in cases of autism in children around the world, according to a growing number of scientists." The report indicates the thimerosal preservative in vaccines is 49.6% mercury, a substance known to have neurotoxic effects.
Croft Woodruff, a Canadian health advocate, points out that the US Food & Drug Administration recommends that pregnant women avoid as much as one can of tuna in a day, which would provide 17 micrograms of mercury. However, the FDA raises no red flag over the 187.5 micrograms of mercury in vaccines given to children from birth to age 6 months. [Letter December 12, 2000] The Environmental Protection Agency has established a safety for exposure to mercury compounds at 0.1 micrograms per kilogram (2.2 pounds) of body weight per day.
Some infants who are being vaccinated using multi-dose vials with thimerosal can receive 62.5 micrograms of mercury per doctor's visit, or 100 times more than the intake considered safe for the average 6-month old by the US Environmental Protection Agency.
Removal of mercury from vaccines
On July 7, 1999 the American Academy of Pediatrics and the US Public Health Service issued a joint statement calling for the removal of thimerosal from vaccines. Their statement admits that chronic, low-dose mercury exposure may cause
neurological abnormalities. [Pediatrics 107: 1147-54, 2001]
While health authorities now have been forced to agree that mercury preservatives be removed from vaccines, the situation is one where current supplies of mercury-laden vaccines are permitted to be used until other preservatives or preservative-free products come into use. [Morbidity Mortality Weekly Report, July 14, 49:
622, 2000]
The removal or reduction of mercury from vaccines has begun. Thimerosal-free hepatitis B, influenza and DPT vaccines are now available. Major vaccine manufacturers have cut the maximal amount of mercury exposure from 187.5 to
75 micrograms. The FDA has announced that the vaccine known as Tripedia (diphtheria, tetanus and pertussis) now has 95% less mercury. [FDA, March 7, 2001] Vaccines for MMR (measles, mumps, rubella) have never contained mercury. Yet health authorities keep recommending vaccines with mercury until preservative-free vaccines are available, stating that the health hazard posed by infectious disease is greater than the side effects from the vaccine. [Clinician Reviews 10: 95-96,
2000]
But the removal of thimerosal increases the potency of the vaccine. Have the new thimerosal-free vaccines been adequately pre-tested?
Vaccines work, but there is a price
A recent news report said that "vaccines are off the hook" in regards to autism. However, Professor Walter O. Spitzer, MD, Professor of Epidemiology at McGill University in Montreal, says the news headlines emanated from a report issued by
the Institute of Medicine Immunization Safety Review Committee, released on April 23, 2001, which claimed vaccines "are as safe as a vaccine can get." Spitzer says the news reporters didn't read the entire report which conceded that "MMR vaccine could contribute to autism in a small number of children." When millions of children are being vaccinated, that could mean thousands of children will be adversely affected. [London Times, May 27, 2001] Translation: the government isn't lying, it's just hiding the headline that there is a strong link between vaccines and autism. The news media in this country isn't digging for the story and is content to parrot government press releases on the subject. Spitzer's comments
were only published outside the US.
For good reason, everyone is afraid of scaring parents away from vaccinations. In 1921 there were 206,939 cases of diphtheria. In 1998, thanks to inoculation, only one case was reported. Measles struck 894,134 people in 1951. By 1998 that figure dropped to less can 100. [Insight Magazine 1999]
Vaccines work, but they have a price. The issue is not whether vaccines cause serious reactions among a small percentage of children, the issue is whether these are avoidable side effects and whether the government is covering their liability, and protecting the profits of the drug companies by not forcing them to dump their stocks of mercury-containing vaccines. The worldwide vaccine market ranges from $2.9 to 7 billion, so vaccines are big business. [Insight Magazine 1999] The drug companies that make the vaccines are immune from legal prosecution. Victims must contact the Vaccine Injury Compensation Program which has awarded more then $1 billion in compensation since it began in 1988. [FedBuzz.com] A $7.50 dose of tetanus vaccine would add $1.50 to the Vaccine Compensation Program Fund. [Salon.com, Ready For Some Lockjaw, March 8, 2001] Only an estimated 1-10 percent of vaccine adverse reactions are reported to the Centers for Disease Control. It is obvious that more reported cases and requests for compensation among families experiencing adverse reactions could bankrupt the compensation system.
What should the public do?
Everybody is pointing fingers, and nobody has any instructions for parents of young children. Parents are confronted with mandates that children be vaccinated or be shunned from entering the public schools. There are paper forms to legally opt out of vaccinations, but that still doesn't solve the problem of what parents should do to protect their children from childhood diseases.
One vaccine at a time
Beginning in 1993 Japan abandoned the MMR vaccine in favor of individual vaccinations for children due to an outbreak of reactions (non-viral meningitis and others).
In Britain, the suggestion that a single vaccine be administered at a time, rather than the triple MMR (measles, mumps, rubella) combination vaccine, has been met with disdain by physicians. Dr. David Sinclair said this would be "pandering to the chattering classes and not to children's health." [News.telegraph.co.uk July 8, 2001] Note the arrogance here from physicians.
In Britain, one doctor who chose to give the MMR in single vaccinations rather than as a combo, is now facing discipline by the Department of Health. [BBC News August 6, 2001]
Barbara Loe Fisher, president of the National Vaccine Information Center in Vienna, Virginia, says vaccines should not be administered to sick children, multiple vaccines in one office visit should be abandoned and re-vaccination among children who have already experienced a reaction should be avoided. [Annals Internal Medicine 133: 661, 2000]
A reason why all children aren't affected by mercury preservatives in vaccines
William Walsh, PhD, of the Pfeiffer Treatment Center in Illinois, has discovered that a defect in the function of a protein called metallothionein is a distinctive feature of autism. This disorder often goes unnoticed in infancy and early childhood, says Walsh, until aggravated by a serious environmental insult. [American Psychiatric Association Annual Meeting, May 10, 2001, New Orleans] Walsh found that 99% of people with autism have a metabolic defect in their ability to handle and dispose of mercury. Among 503 autistic people, 499 were unable to produce metallothionein, a protein compound that binds to heavy metals in the body like mercury as well as cadmium, lead, copper, iron and zinc. Walsh's study explains why every child who undergoes vaccination does not develop autism. The London Times placed Walsh's report on its front page but American newspapers passed up the opportunity to publish the results of his study, as if working
in lock step to keep the lid on the link between mercury and autism.
Metallothionein is rich in sulfur and a sulfur compound called cysteine. Metallothionein binds to potentially toxic metals, but these metals can be jarred free during states of inflammation, infection or disease, and induce rusting of tissues (oxidation). [Archives Biochemistry Biophysics 363: 171-81, 1999] Metallothionein is produced throughout the human body but is concentrated in liver, kidneys, intestine and the pancreas and only occurs in small amounts in the blood circulation and brain. [Progress Food Nutrition Science 11: 1-37, 1987]
Boost metallothionein
Walsh advocates stimulation of metallothionein with zinc and manganese and by the provision of a sulfur-bearing amino acid, cysteine. Also on Dr. Walsh's nutrient list is vitamin B6, vitamin C, selenium and vitamin E.
A dietary sulfur deficiency results in a deficiency of metallothionein. [Experientia 34: 281-91, 1979] Eggs, garlic, asparagus and onions are sulfur-rich foods. The provision of cysteine, a sulfur-rich amino acid, increases the production of metallothionein. [Journal Pharmacology Experimental Therapy 255: 554-64, 1990]
Vitamin C increases metallothionein levels in the liver. [Toxicology 43:
251-59, 1987; 85: 85-100, 1993] Vitamin C reinvigorates the action of glutathione, a major antioxidant in the body. When synthesis of glutathione is low, more metallothionein is produced. [Biometals 6: 171-78, 1993] These metal defense systems back up each other. When one fails, another other takes over.
Mercury wastes or uses up selenium, a trace mineral that combines with vitamin E to produce an important antioxidant enzyme in the body called glutathione peroxidase. Selenium protects from mercury poisoning. [Annual Review Nutrition 17:
37-50, 1997] Selenium seems to protect against metal poisoning through methods other than metallothionein. [Journal Toxicology Environmental Health 38: 171-82, 1993; American College Nutrition 61: 646-50S, 1995]
Metallothionein has a working relationship with vitamin E. When vitamin E levels are low, more metallothionein is produced. [European Journal Nutrition 39: 112-20, 2000] Again, these nutrient systems back up each other to protect from unbound
metals being introduced into the system.
Bioflavonoids are metal-binding pigments found in grapes, berries and citrus fruit that can take the place of metallothionein. [Biology Trace Element Research 62: 135-53, 1998]
Importance of zinc
Dr. Walsh also says that a relatively high ratio of copper over zinc results in children who are hyperactive, who have attention deficit and poor behavior control. High copper ratios also lead to estrogen dominance in adult females
which leads to depression and irritability.
Studies suggest that infants and children may be at risk to develop subtle developmental delay if they do not receive sufficient zinc in the first few years of life. Metallothionein accumulates when tissues are exposed to excess zinc and is depleted in states of zinc sufficiency. [Journal Nutrition 126: 11782-90, 1996]
Zinc deficiency induces a shortage of metallothionein. [Proceedings National Academy Science 87: 1259-62, 1990] Dietary zinc deficiency impairs metallothionein levels in the brain. [Neurochemistry International 36: 555-62, 2000] Levels of
metallothionein in the liver are highest among newborn infants and fall at around 4 months of age. [Pediatric Research 24: 326-29, 1988]
The role of essential fats in autism
The red blood cell level of unsaturated fats, primarily the omega-3 fats obtained in the diet from fish and flax seed, is low among autistic, attention deficit and dyslexic children. [Prostaglandins Leukotrienes Essential Fatty Acids 63: 21-25, 2000] A recent study found markedly reduced levels of omega-3 fatty acids among 23 percent of autistic subjects compared to mentally retarded children, who often have low omega-3 fatty acid levels themselves. [Prostaglandins Leukotrienes Essential Fatty Acids 65: 1-7, 2001]
Serotonin and autism
Serotonin is a relaxing brain chemical that is involved in mood and in autism. During normal childhood, humans undergo a period of high brain serotonin production, a process that is disrupted in autistic children. [Annals Neurology 45: 287-95, 1999] Most autistic individuals treated with serotonin transport
inhibitors exhibit a reduction in ritualistic behavior and aggression. [Current Opinion Pediatrics 8: 348-54, 1996]
An amino acid called tryptophan, supplied in the diet, is required for the production of serotonin. Autistic people exhibit a significantly lower ratio of serum tryptophan compared to other neutral amino acids (proteins), which means less tryptophan is available to brain tissues in these subjects. [Biomedical
Pharmacotherapy 49: 288-92, 1995] Studies reveal that a low-tryptophan diet increases behaviors such as banging and hitting self, rocking, pacing, and anxiety among autistic individuals. [Archives General Psychiatry 53: 993-1000, 1996]
Tryptophan-rich foods encourage the production of serotonin, the brain chemical lacking in autistic people. [Advances in Pediatrics 33: 23-47, 1986]
Foods which have the highest amounts of tryptophan (serotonin production qualities) are (in order): dates, papaya, banana, strawberries, cherries, pineapple, grapefruit and figs. [American Journal Clinical Nutrition 71: 1669-75S, 2000]
A deficiency of niacin (vitamin B3) often accompanies serotonin deficiency since both serotonin and B3 are composed of tryptophan. In a state of vitamin B3 deficiency more tryptophan is needed to make this vitamin and less remains
to be transformed into serotonin. So niacin may be added to a food supplement list for autistic people.
The best diet is not good enough
It is easy to see here that a decline in the nutrient value of foods may underlie the increased rate of autism. Comparisons of food values by the US Department of Agriculture from 1963 to the present reveals many plant foods do not provide the
nutrients they once did. Furthermore, the insistence by health authorities that children consume 5 servings of fresh fruits and vegetables daily is unlikely to be met by young children who have fussy food preferences. [Nutrition Reviews 59: 224-35, 2001] Eight of ten young children simply do not consume sufficient amounts of plant foods. Research conducted at the University of California at Berkeley reveals that nutritional deficiencies can result in damage to DNA genetic material similar to what results from over-exposure to atomic radiation. [Mutation Research 475: 7-20, 2001] The diet simply is not adequate to provide optimal defense against disease.
The mass use of food supplements (vitamin pills) by young children is called for, but this practice is unlikely to be advocated by health authorities. Nutritionists continue to insist that children (and adults) can obtain all the nutrients they
need from their diet. This may be true if a parent is trying to prevent scurvy and rickets in their children. Food fortification also goes a long way in preventing deficiency diseases. But then again, young children are unlikely to eat the proper foods, particularly raw fruits and vegetables that have not lost nutrient value
due to cooking and processing. The consumption of the recommended five servings of fresh fruits and vegetables daily has never exceeded 23% among US adults, let alone young children. [American Journal Public Health 90: 777-81, 2000] A survey of American school-age children, 7-12 years of age, found that 12-13% consumed less than 30 milligrams per day of vitamin C. [Journal American College Nutrition 18: 582-90, 1999] Furthermore, the amount of vitamins and minerals provided by the
diet is not sufficient to withstand the universal assault on the immune system posed by vaccines.
Ranges of nutrients in food supplements for children:
Vitamin C: should be the buffered (alkaline) form of vitamin C (not ascorbic acid) which is already chelated (attached to) minerals. Supplemental dosage should exceed 100 milligrams per day for young children. Provide 200-300+ milligrams per
day in the days surrounding vaccinations. Watery stools can result from vitamin C overload.
Vitamin E: Should be from natural-source vitamin E as d-alpha tocopherol
succinate. Dosage: 15-30 IU
Niacin: 5-10 milligrams per day for young children.
Zinc: poorly absorbed from most foods. Food supplements should provide
about 4-6 milligrams for kids.
Selenium: This trace mineral should be obtained in its organically-bound
form (brand name, SelenoExcel). Dosage: 15-40 micrograms.
Vitamin A: The measles vaccine reduces blood serum levels of vitamin A.
[Acta Paediatrica Japan 40: 345-49, 1998] Dosage: 2500 IU as vitamin A palmitate
Omega-3 fatty acids: Preferably should be provided from fish oil that provides DHA, the type of fat that insulates neurons in the brain and nervous system. Flaxseed oil is usually preferred by children because of its taste, but it has to be converted in the liver into DHA for use by nerve cells. Flaxseed oil is probably the best alternative for young children. Normal and autistic children require supplementation with omega-3 fats since the American diet is deficient in these essential fats. Dosage: 1000-2000 milligrams per day.
The diet should be rich in bioflavonoids from grapes, berries and citrus fruit and in sulfur from eggs and asparagus.
Magnesium and vitamin B6: Children with seizures and autistic behavior probably ought to be provided supplemental magnesium and vitamin B6. [Journal Childhood Neurology 15: 763-65, 2000] While magnesium and vitamin B6 therapy for autism has more recently been discredited, the fact that a 1988 survey of parents of autistic children found this nutrient combination more helpful than drugs cannot be ignored. [Journal Childhood Neurology 3: 68-72S, 1988] Apparently both vitamin B6 and magnesium are required in combination to produce behavioral and biochemical changes in autistic children. [Biological Psychiatry 20: 467-78, 1985] The side effect of excess magnesium is loose stool which is remedied by reducing the dosage. Of interest, magnesium therapy is less effective among older adults with tetanus infection. [Anaesthesia 54: 302-03, 1999]
Good bacteria: acidophilus-bifidus supplements are likely to be helpful in cases of existing autism. New brands that offer live refrigerated acidophilus bacteria (Bio-K Plus) may be a breakthrough in this approach to therapy.
There is argument over dietary approaches for autism. All of the above measures, even foods, should be introduced to autistic individuals in small doses, with careful observation. Dietary programs need to be tailored to the individual. For
example, anemic children (who often have cold hands and feet because of a lack of red blood cells as well as fatigue) may not benefit from foods or supplements that chelate minerals. Whereas children with toxic metals in the brain may benefit from
chelation and iron supplementation would worsen symptoms. Children with low-grade tetanus infection in the digestive tract may benefit from acidophilus supplements. Attempts should be made to tailor diets and supplements around what is observed to work.
Chelation for children or adults who are already autistic
There is hope that metal chelation may be therapeutic for autistic kids. A number of alternative medical clinics perform intravenous chelation therapy using EDTA as a metal chelator, but there is little documented evidence of its effectiveness.
Some people in the know estimate two thirds of autistic children improve after chelation therapy.
Chelation can be safely performed at home. Nature's strongest natural metal chelator is phytic acid, obtained from rice bran and available as a food supplement called IP6 in health food stores. [Cancer 56:717-718, 1985] Phytic
acid can be taken in low doses, 200-1000 milligrams for children, with water only (no juice) in between meals, so as not to interfere with minerals in the diet. Parents should provide young children with a magnesium mineral supplement, 50-100
milligrams, to balance the calcium found in the rice bran. In a course of 10-30 days chelation would be complete. Since phytic acid is a component of whole grains and rice bran extract has been used as a food supplement by many thousands of
people, it is not expected to be troublesome in a short course. Prolonged use might induce iron-deficiency anemia. IP6 rice bran extract should not be used among anemic individuals or pregnant females. The case of a 4 1/2-year old autistic boy with elevated levels of lead in his blood circulation whose hyperactivity improved upon removal (chelation) of the heavy metal (but returned with discontinuation of treatment) is evidence that chelation therapy may be promising for some autistic children. [Molecular Medicine 93: 136-38, 1996]
Other food supplements that may be helpful for children with metal overload are alpha lipoic acid (sulfur compound) and bioflavonoids (such as grape seed extract, elderberry, cranberry, etc.).
All humans of every age are prone to metal toxicity, particularly in their nervous system and brain. Chelation of metals from the brain and nervous tissues may be therapeutic to adults with brain disorders. The case of a 47-year old dentist who
developed Parkinson's disease and experienced improvement with the use of a mercury chelating drug serves as an example of this approach. [Neurotoxicology 17: 291-95, 1996]
Digging deeper
The sole cause of autism is probably not mercury poisoning. Developmental problems, hormones and other unknown factors are likely to be involved. Recall that autism strikes far more boys than girls, which goes unexplained (see below). A recent survey found 83% of autism cases were among boys. [British Medical Journal 322: 460-63, 2001] Between the ages of 2 to 4 years, one study found autistic boys had a brain volume larger than normal. [Neurology 57: 245-54, 2001] Autistic children are more likely to experience painful oversensitivity to sound. [Journal Autism Developmental Disorders 29: 349-57, 1999] Autistic children may have more visual problems, particularly farsightedness, astigmatism and crossed eyes. [Journal French Ophtalmologie 20: 103-10, 1997] Autoimmune factors may interfere with the thyroid hormones in young autistic children. [Journal Child Psychology Psychiatry 333: 531-42, 1992] Premature infants who develop blindness of prematurity (retinopathy) are more likely to exhibit autistic behavior. [Developmental Medicine Childhood Neurology 40: 297-301, 1998] But these children are observationally autistic from infancy, and don't fit the common pattern of onset around the age of 3. Yet many birth-related developmental disorders do not emanate early but rather materialize in the second to fourth years. Other factors must be explored.
Premature birth
Premature birth is associated with (not necessarily the cause of) autism. In one study of 77 babies who were born at the 23rd week of gestation and survived, 34% had severe disability defined as subnormal cognitive function, cerebral palsy,
blindness and/or deafness, a pattern that is strangely similar to those found in autism. [Seminars Neonatology 5: 89-106, 2000]
Premature birth is defined as birth before 37 weeks of gestation. Due to modern medical technology, survival has increased significantly in extremely premature infants. For example, at Washington University, St. Louis, the survival rate of infants weighing less than 800 grams (1 lb 12 oz) at birth increased from 20% in
1977 to 49% in 1990. [American Family Physician Website, May 1 1998] Among 5271 infants cared for in a Japanese hospital neonatal department, 18 developed autistic disorder and the incidence was 34 per 10,000 (0.34%), which was twice
the highest rate previously reported in Japan. [Journal Autism Developmental Disorders 29: 161-66, 1999]
Infants born prior to 25 weeks of gestation are more likely to exhibit severe disabilities if they survive. [New England Journal Medicine 329: 1597-1601, 1993] Among 568 babies born prematurely between 23-26 weeks gestation, only 4 were free
of major handicap at 2 years of age. [Obstetrics Gynecology 82: 1-7, 1993] The fact more low-birth weight children survive today could account for a percentage of the autism growth rate. The public is generally uninformed by educational groups about the link between premature birth and autism.
The prevalent opinion is that there is no conclusive evidence that premature birth is linked to autism. But this topic is poorly studied. One study found the factors associated with autism are low birth weight, late start of prenatal care, and previous termination of pregnancy. [Journal Perinatal Medicine 27: 441-50, 1999]
Because of widespread population control efforts, it is likely that the association between terminated pregnancy (abortion) and autism is politically incorrect.
How to prevent prematurity
There are measures that pregnant women can take to prolong pregnancy and encourage full-term babies. Prematurely-born infants have less circulating omega-3 fats than full-term babies. [Sb Lek 94: 19-24, 1993] Deficiencies of omega-3 fatty acids have been linked with premature birth and low-birth weight babies. In one study, women who ate eggs fortified with omega-3 fats had no low-birth weight babies versus 13% low birth weight babies among women consuming small amounts of omega-3 fats. Only 6% of babies were delivered pre-term by mothers who consumed omega-3 fortified eggs versus 25% in the group that consumed regular eggs. Fish oil consumption (2700 milligrams per day providing at least 500 milligrams of DHA) is now recommended during pregnancy. [Obstetric & Gynecologic Survey 56: 1-13S, 2001]
In 1997 researchers reported an association between high vaginal pH (alkalinity) and premature birth, a problem that can often be corrected by the provision of good bacteria (lactobacillus acidophilus) treatment. [Journal Perinatal Medicine 25: 406-17, 1997]
Other risk factors for prematurity are smoking and drug use. [Epidemiology 11: 427-33, 2000]
Autism and the tetanus toxoid vaccine
The theory that tetanus is a cause of autism was first proposed by E.R. Bolte in 1998. Everyone probably thinks of tetanus as lockjaw and tetanus shots as prevention against an infection one gets from rusty nails. Actually, tetanus is a
prevalent pathogenic bacterium that can infect the umbilical cord after birth and cause the death of a newborn baby as well as the mother. Neonatal tetanus infections are common in undeveloped areas of the world where untrained midwives cut umbilical cords with razor blades or other un-sterile instruments.
Researchers theorize that a chronic, sub acute tetanus infection of the intestinal tract could gain hold in the human gastric tract that has been over-exposed to antibiotics drugs which have killed off protective bacteria. Tetanus may eventually enter the nervous system and make its way to the brain where it has been shown to disrupt the release of brain chemicals which can produce altered behavior. This has been demonstrated in laboratory animals injected with tetanus in the brain. Some children with autism have also shown a significant reduction in abnormal behavior when treated with antibiotics that kill off the Clostridium tetani bacterium. [Medical Hypotheses 51: 133-44, 1998]
Links between tetanus and autism: sex ratio
Some compelling evidence links tetanus with autism. First, recall that the sex ratio for autism is about 3 boys for every affected girl. For example, a ratio of 4.2 to 1 boys over girls was found in autistic care facilities in Israel, which is typical of the ratio around the world. [Israeli Medical Association Journal 3:
188-89, 2001] This same ratio unexplainably occurs in the percentage of newborn boys and girls who experience tetanus infection. In a Turkish hospital, among 133 newborns being treated for neonatal tetanus, 79 were males and 56 were females.
[Scandinavian Journal Infectious Disease 25: 353-55, 1993] Another Turkish study reveals that 74% of neonatal tetanus cases admitted to a hospital in Istanbul were males. [Turkish Journal Pediatrics 34: 121-25, 1992] In Thailand, the ratio of
male to female neonatal tetanus cases was found to be 1.5 to 1.0. [Journal Medical Association Thailand 72: 638-42, 1989] In a 1976 study in Mexico, the ratio of males over females with neonatal tetanus was 4.62 to 1. [Bol Med Hospital Infant
Mexico 33: 465-71, 1976]
Links between tetanus and autism: season of onset
A similar parallel exists for the season of birth, autism, and tetanus infection. Tetanus infection is known to peak in the Spring and midsummer. A Swedish study showed a peak for autism among births occurring in March. [Acta Psychiatrica
Scandinavia 82: 152-56, 1990] An Israeli study shows an increase in autism among March and August births. [American Journal Psychiatry 152: 798-800, 1995] A study in Boston also shows a seasonal peak in March for autism. [Journal Clinical Experimental Neuropschology 22: 399-407, 2000]
Links between tetanus and autism: magnesium and vitamin B6
Another intriguing triad is that of magnesium/vitamin B6 therapy, tetanus and autism. As previously cited, numerous studies indicate magnesium and vitamin B6 may be helpful in relieving symptoms of autism. [Biological Psychiatry 20: 467-78, 1985]
Magnesium and vitamin B6 are also used in the treatment of spasms (lockjaw) caused by a tetanus infection. Magnesium is a smooth muscle relaxant. Intravenous magnesium has been successfully used to treat severe spasms of tetanus without the
need for sedative drugs or artificial ventilation. [Anaesthesia 52: 956-62, 1997; Annals Academy Medicine Singapore 28: 586-89, 1999]
Vitamin B6 works to make magnesium more active and bio-available. Vitamin B6 reduces the mortality rates among infants with tetanus infection. [Journal Infectious Diseases 145: 547-49, 1982] In one study, the mortality rate among neonates with tetanus infection given vitamin B6 orally along with drugs was 38%
versus 60% among drug-treated only children. [Paediatrica Indonesia 31: 165-69, 1991]
Some parents have bathed their children in water with added Epsom salt which is rich in magnesium and have achieved some improvement in behavior and language skills. [Pervasive Developmental Disorders: finding a Diagnosis and Getting Help,
Mitzi Waltz, 1999 at www.patientcenters.com]
The use of magnesium and vitamin B6 among autistic people was dismissed after a 1997 study found the combination therapy to be ineffective. But the study utilized an unusually high dose of vitamin B6 which would likely cause nerve side effects and a relatively-low dose of magnesium in its poorest-absorbed (oxide) form. [Journal Autism Developmental Disorders 27: 467-78, 1997]
Three intriguing findings: the sex ratio of autism, season of onset, and magnesium/vitamin B6 therapy for autism, parallel each other. Are these findings just coincidence?
Is tetanus vaccine a risk factor for autism?
The general belief is that tetanus toxoid vaccination during pregnancy affords protection for mother and baby and poses no risk to either party. [Clinical Infectious Disease 28: 219-24, 1999] Tetanus toxoid vaccine is administered in the 3rd trimester since transfer of immunity from mother to baby occurs late in
pregnancy. [Nature Medicine 5: 427-30, 1999] The World Health Organization says the last dose of tetanus vaccine should be administered to pregnant females at least 2 weeks before delivery. [World Health Organization]
Of 3+ million babies injected with the tetanus-containing DPT vaccine annually, over 33,000 will experience acute neurological reactions, which includes 8500 cases of convulsions and 16,000 instances of high-pitched screaming.
There is no question that the tetanus vaccine reduces infection and neonatal death. In the early 1900s about 1500 people contracted tetanus each year then. The vaccine apparently reduced tetanus to 500-600 annual cases into the 1940s, and
thereafter tetanus cases dropped to fewer than 70 annually.
In 1900 about 64 of every 100,000 infants less than 1 year of age died of tetanus, most shortly after birth due to improper umbilical cord care. Since 1989 only 2 cases of tetanus in newborns have been reported in the US. An estimated 300,000
cases of neonatal tetanus infection occur annually, most in undeveloped areas of the world. A relatively large percentage of the US population has not been vaccinated against tetanus, yet where are all the tetanus cases from rusty nails?
Doctors in the Netherlands have reported a case of transient Parkinsonism in a 38-year old metal worker after he had received the last of 3 tetanus vaccinations. [Journal Neurology Neurosurgery Psychiatry 63: 258-59, 1997]
Irregularities in tetanus vaccines
Tetanus spores are scattered everywhere and are so tough they easily tolerate antiseptics or being heated to 250 degrees Fahrenheit for 10-15 minutes. Tetanus lives in soil, the bowels of animals and humans, and is only dangerous when it
enters a wound and is deprived of oxygen which ignites its replication and then gives off toxins that block nerve impulses for muscle relaxation, resulting in spasms. [Vaccinating Your Child: Questions & Answers for Concerned Parents, Peachtree Publishers, 2000, at www.kidsdirect.net]
To understand how tetanus, or the tetanus toxoid vaccine, may induce autism, a working knowledge of how the vaccine is made and how it works is called for. The vaccine is composed of toxoids of tetanus (toxins emitted from organisms) and
cultured in beef heart infusion along with sugar, salt and milk by-product. The broth is then filtered and formaldehyde added (embalming fluid) along with aluminum compounds. Once inside the human body the formaldehyde coating dissolves and releases all bacterial and viral particles.
Troubles have occurred with the tetanus vaccine from its first production in 1924.
Dr. Kris Gaublomme says "infections and intoxications due to mistakes in the production of the vaccine have played a role since the beginning of its development. Due to technical failure, particles of tetanus remained in the vaccine fluid causing illness and death. The use of certain soils makes it
possible that the concentration of formaldehyde is insufficient, so that un-detoxified toxoid remains."
Furthermore, tetanus vaccines (or any vaccines for that matter) are not standard from one manufacturer to another. A landmark 1985 report indicated the nation is vulnerable to interrupted supply of vaccines like tetanus due to stability
problems, variation in potency, or contamination. [Vaccine Supply and Innovation 1985, National Academy of Sciences]
In 1984 two of the three companies producing DPT vaccines (diphtheria/pertussis/ tetanus) ceased distribution, citing problems with liability exposure the cost of insurance premiums. That led Congress to establish the vaccine compensation
fund. But production problems still persist and the Centers for Disease Control announced this past year that Wyeth-Ayerst, one of two US manufacturers of tetanus vaccine, would withdraw its product from production.
For a time, a limited supply of tetanus vaccine is available in the US. It will be interesting to monitor any slow down in childhood tetanus vaccinations to see if an accompanying drop in the rate of autism also occurs. A slow down in the tetanus
vaccination rate may not occur among newborns or pregnant females however since the CDC directives recommend pregnant women who haven't been vaccinated within the past 10 years should have priority access to tetanus vaccine. [American Medical Association April 11, 2001]
To add to the intrigue, Wyeth-Ayerst claims it ceased production of its tetanus vaccine for purely business reasons, but the FDA raided a Wyeth warehouse and seized various products including tetanus/diphtheria vaccine. Later, an FDA spokesperson indicated she was wrong in indicating tetanus vaccines were seized from Wyeth, but Wyeth-Ayerst says the seizure involved various products including
tetanus/diphtheria vaccine. The FDA says vials of the vaccine were released into the marketplace, whereas Wyeth-Ayerst says they never got that far. Both parties say the vaccine was never a risk to public health. Apparently it wasn't the vaccine itself, but its packaging that was at fault. [Salon.com, Ready For Some Lockjaw, March 8, 2001] Question: was the Wyeth tetanus vaccine contaminated via small punctures in the packaging that permitted contamination with the Clostridium tetani bacterium itself? The public has no access to data on which brands of vaccines have been administered to autistic kids. One wonders if there is a link between autism, tetanus inoculation and a particular brand of the vaccine?
Recall that it was Wyeth-Ayerst who introduced its Rotavirus anti-diarrhea vaccine with an intense advertising campaign, induced widespread usage (over 1 million children were administered the vaccine), but was forced to withdraw the product
shortly after its introduction because of cases of bowel obstruction that ended up to be deadly for a small number of children. Also recall that Wyeth-Ayerst had to recall its fen-phen diet drug when it was found to cause heart problems that cost the company $3.7 billion in damages.
How often to vaccinate?
Furthermore, how often to vaccinate with a tetanus booster is simply guesswork. Apparently too much of this vaccine can backfire. Tetanus toxoid appears to afford protective effect up to 3 or more years following vaccination. However, in Tanzania researchers have reported that the serum antibodies against tetanus toxin in 7 neonates who were infected with tetanus were found to be 4-13 times higher than the presumed protective level. All but one of the mothers had been vaccinated with tetanus toxoid in pregnancy. Two mothers who had received booster doses during pregnancy had anti-toxin concentrations 100-400 times the presumed protective level. The toxin dose may overwhelm the pre-existing anti-toxin level and produce disease and lead to an ineffective immune response. [FEMS Microbiology Immunology 3: 171-75, 1991]
Attempts to make tetanus vaccine a population control agent
There are more disturbing reports surrounding the tetanus vaccine. The American Life League reports that the World Health Organization (WHO) spent over $356 million for women's reproductive health, in part to develop a vaccine against
pregnancy. WHO covertly added human chorionic gonadotrophin (HCG) hormone, which is essential to maintain pregnancy, to tetanus vaccines and administered them to women of childbearing age in Mexico, Nicaragua and the Philippines. Upon pregnancy antibodies will not only be formed against tetanus but also to HCG which would then cause a spontaneous abortion. High levels of HCG were detected in 27 of 30 vaccinated women tested. Cases of miscarriage were reported. Every time an inoculated woman would get pregnant her immune system would prompt a miscarriage (abortion). This story was aired by the British Broadcasting Corporation in 1995 and verified by the Philippine Department of Health and the Philippine Medical Association, but was never aired in the USA.
Dr. Jong-Wock Lee, director of the the World Health Organization (WHO)Global Programme for Vaccines and Immunization, called these charges nothing but rumors without scientific basis. The positive HCG hormone in the tetanus vaccine was called an "artifact" and dismissed. WHO said tests from tetanus toxoid samples from Mexico and Tanzania were negative or of "no significance." [WHO Press release July 19, 1995] The last two words are alarming, since no trace amount of the hormone should even exist in vaccines.
More trouble: the MMR vaccine
Tetanus vaccine is not the only vaccine under scrutiny. Both the Centers for Disease Control and the vaccine manufacturers warn that the MMR vaccine (a live viral vaccine) should not be given to pregnant women. However this vaccine is often required and administered for employment or work around children and may be administered to fertile females around the time of conception. Dr. F. Edward Yazbak reports on a small group of seven women who received an MMR or Hepatitis B vaccine booster five months prior to conception. All of the children from these pregnancies were autistic or autistic-like behavior. In a different series of 22
mothers who had received a live-virus vaccine prior to conception, every one has had at least one child who is autistic. [Idaho Observer, June 2000]
A startling report from Japan conclusively links the MMR vaccine with cases of autism. Researchers at Tokyo Medical University noted onset of autism in some cases soon after administration of the MMR vaccine. Cases of autistic children with chronic intestinal inflammation were examined to determine if the measles virus was present. Three of nine children with autism exhibited the measles virus and genetic testing determined they were from vaccine strains of the virus, not wild strains. [Digestive Disease Science 45: 723-29, 2000]
The CDC says: "Generally, live-virus vaccines are contraindicated for pregnant women because of the theoretical risk of transmission of the vaccine virus to the fetus. If a live-virus vaccine is inadvertently given to a pregnant woman, or if a woman becomes pregnant within 3 months after vaccination, she should be counseled about the potential effects on the fetus. But it is not ordinarily an indication to terminate the pregnancy." [Guidelines for Vaccinating Pregnant Women, Centers for Disease Control, October 1998] Veterinarians are advised to avoid vaccinations to pregnant dogs, and if required, only with killed vaccines. [Veterinary Teaching Hospital, Virginia Maryland Regional College Veterinary Medicine]
The list of vaccines that are permitted by the CDC to be administered to pregnant females includes hepatitis B, influenza, tetanus/diphtheria, meningococcal and rabies. Given that government sources of information about the safety of vaccines are in question, any vaccines administered to pregnant females should be seriously questioned. Universal vaccination based upon statistical risk analysis should be abandoned in favor of careful evaluation of individual risk factors.
With all of the efforts to vaccinate and prevent disease, premature infants receive lower doses of passive maternal antibody and may not be protected regardless of maternal levels of specific antibodies. [Clinical Perinatology 24: 231-49, 1997]
Public confidence in nation's vaccination program is waning
The public confidence in the information being supplied to them about vaccines is waning. Within 10 years of the introduction of the polio vaccine, cases of polio dropped from 30,000 to less than 1000 per year, a stunning success for vaccines. But about a third of the vaccine was contaminated with a monkey virus (SV40)
which was discovered in 1961, a few years after the introduction of the vaccine. About 30 million Americans (100 million people worldwide) have been given injections of the contaminated vaccine which is now being linked to a once rare form of cancer that now causes 2000-4000 cases of mesothelioma chest cancer annually. [San Francisco Chronicle, July 15, 2001; Atlantic Monthly, February 2000]
The Food & Drug Administration bungled the rotavirus vaccine. Rotavirus affects most young children with symptoms of diarrhea which may require hospitalization and result in 20-40 deaths annually. In 1998 the FDA approved RotaShield, the
vaccine against rotavirus. Pre-release data showed a 30 times increased rate of intestinal blockage with the vaccine but it was still recommended for all infants in 1999. Faced with evidence the vaccine was causing trouble, the CDC later withdrew its recommendation for the vaccine. Among the 1 million children who had
been inoculated with Rotashield, two died and 99 cases of bowel obstruction were reported. [Free Market Newsletter, April 2001]
Last year the American Academy of Pediatrics suggested doctors cease using the oral polio vaccine and use the injected form which does not contain any live viral particles. Roughly 5 children a year develop polio from the Sabin oral vaccine.
[HealthScout, December 7, 2000] Live polio vaccine has been stopped because it turned out to be the sole cause of the disease!
Timothy D. Terrell, writing in The Free Market newsletter [Mises Institute], notes that among 4 million births every year, only about 50 children will contract hepatitis B before their first birthday, typically because the mother has the virus. For children under the age of 14, the incidence is about 2-6 cases per million, which means that children are three times more likely to die or suffer adverse reactions from the hepatitis B vaccine than the disease itself. The hepatitis vaccine used to be recommended shortly after birth, but now is recommended prior to age 6 months. Terrell reveals that several members of the CDC advisory panel on vaccines hold drug company stocks and stand to profit from
their decisions.
Good bacteria and development of the infant immune system
Autoimmune reactions and brain viruses may also be involved in some cases of autism. Other autoimmune diseases such as arthritis have been associated with vaccinations (tetanus toxoid, influence, polio and others). [Journal Autoimmunity 14: 1-10, 2000]
Teresa Binstock, a researcher in developmental and behavioral neuroanatomy, describes how the infant immune system develops. A species of B-cells (B stands for being produced in bone marrow) called CD5+ are among the first to appear in
the developing embryo and play an important role in the digestive tract. Neonates have very limited good bacteria (microflora) and are susceptible to colonization by pathogenic bacteria during the days and months following birth. The administration of antibiotics further kills off beneficial and protective bacteria. Undesirable bacteria can release toxins that disrupt normal gut wall permeability and permit their migration to the central nervous system. A sub-acute
Clostridium tetani (tetanus) infection in the gastrointestinal tract early in life, as an infant's CD5+ B-cells were being established could result in the immune system thinking the tetanus bacterium as "normal." Thereafter the immune system would only mount a poor effort to eradicate it. Sub-acute tetanus
infection may forever be experienced by those affected. Antibiotics could kill off the Clostridium tetani bacteria, but good bacteria would need to be replaced after such therapy. Babies are initially inoculated with bacteria from their mother's
vaginal and fecal flora during birth. Following birth, breast feeding appears to encourage the growth of friendly acidophilus-bifido bacteria while bottle-feeding appears to encourage a wider range of bacteria including Clostridia tetani.
Protect the gastrointestinal tract
Autistic children often exhibit gastrointestinal troubles. Gastric distress followed by bloody stools is often reported. Antibiotics are indiscriminate in their elimination of bacteria, friendly or unfriendly, from the gut. After a course of antibiotics a child's digestive tract is vulnerable to opportunistic
bacteria that may take up residence. Decades ago doctors provided good bacteria after antibiotic therapy but for some reason this practice was abandoned. If pathogenic bacteria take up residence in sufficient numbers they may break down the protective wall in the gut and permit undigested food particles to enter the system which results in a food allergy response, and for the entry of neurotoxins which affect the brain by altering the production of serotonin.
Both tetanus and botulinum bacteria belong to the bacterial genus Clostridium form and release spores that produce toxins which can pass through the gut wall and block the release of nerve chemicals, resulting spastic paralysis. [Annals Pharmacy France 59: 176-90, 2001] Of interest, components of black tea (thearubigin) protect against the nerve toxic effects of tetanus. [Experimental Biology Medicine 226: 577-80, 2001]
The use of acid-forming probiotics like acidophilus have been proven to prevent diarrhea following antibiotic use. [International Journal Antimicrobial Agents 16: 521-26, 2000; Journal Pediatrics 135: 564-37, 1999] Every parent needs to become familiar with probiotic products and administer them to their children following antibiotic therapy since the medical profession has overlooked this practice.
There is growing concern over the problem of antibiotic resistance. The overuse of patentable antibiotic drugs has given rise to mutated germs that are resistant and which now pose a threat to life. [Clinical Infectious Diseases 33: 124-29S, 2001]
There are various naturally-occurring antibiotics that provide broad spectrum protection from pathogenic bacteria, viruses and fungi. Some of these are oil of oregano, olive leaf extract and garlic, and germs cannot mutate and develop
resistance against them. [Journal Food Protection 64: 1019-24, 2001; Journal Applied Microbiology 85: 211-18, 1998; 86: 985-90, 1999] Use of these naturally-occurring antibiotics needs to be explored as they may prevent plagues that could at some time in the future sweep through human populations.
Final notes
Be wary of what you read about autism from official sources. There is too much money, liability, and conflict of interest to obtain the truth from most governmental and health authorities. The news media is either lazy or over-cooperating with government under the guise of maintaining public confidence in vaccines. Healthy skepticism and careful investigative work is required to unveil the many hidden facts that still surround the terrible and apparently avoidable tragedy of autism in America.
A government report states that "the federal government has responded to concerns about the safety of vaccines through several mechanisms.... In 1986 Congress passed the Vaccine Compensation Amendments as part of the National Childhood Vaccine Injury Act." [Immunization Safety Review, National Institute of Medicine] Typical of politicians, they protected the liability of the vaccine manufacturers
and think that paying off parents for permanent side effects in their children is sufficient. There is an epidemic rise in the occurrence of autism and nobody is doing anything about it.
It is often said that innovation in any field springs outside its ranks. Ellen Bolte, a mother of an autistic child, was the first to propose a link between tetanus and autism. [Amednews.com, American Medical Assn, August 14, 2000; Medical Hypotheses 51: 133-44, 1998; Autism Research Review 12: No. 4, 1998] Tetanus infection appears to have strong linkages to autism. Working on Bolte's hypothesis, Richard H. Sandler MD, director of pediatric gastroenterology at
Rush Children's Hospital in Chicago, conducted a short-term study upon 11 autistic children with Vancomycin, an antibiotic drug. Ten of the children experienced dramatic improvement in behavior and social skills but symptoms returned with
cessation of therapy. This small study appears to confirm that link between gastric/brain infections and autism. [Journal Childhood Neurology 15: 429-35, 2000]
It is unlikely that the research community or the drug companies will come up with a cure for autism. Researchers attempt to turn a research project into a career and often only conduct narrow studies that are fixed on understanding the mechanisms of a disease or how to diagnose it rather than find a simple, inexpensive cure. Physicians are too dependent upon pharmaceutical companies to bring them the cures for their patients. The market for a cure for autism is too small to attract a drug company, even with the orphan drug act. Special people will have to step forward, like parents of autistic children, and venture into finding the way out of autism on their own. A July 2001 Gallup poll reveals that 94 percent of the public believes childhood vaccination is important. Information about the drawbacks of vaccination had reached 39% of the public. Only 6 percent of those polled believed vaccines were more dangerous than the diseases they were designed to prevent.
There is hope
This paper uncovers evidence of at least two origins of autism, vaccines and the over use of antibiotics which can result in the growth of pathogenic bacteria in the digestive tract. Thus, while the behavioral symptoms of autism may be similar, as both tetanus toxins, or heavy metals like mercury, may alter brain chemicals
(serotonin), therapeutic approaches to these children need to be carefully tailored around the origin of their disease. Metal chelation may be appropriate for one group, and antibiotic/probiotic therapy may be indicated for another.
There is hope for autistic children. In a 1979 report, a set of twins exhibited early infantile autism, but for unknown reasons one of the children spontaneously improved at the age of 4. [South African Medical Journal 55: 955-57, 1979] The disease is not necessarily locked in.
Bill Sardi is a health journalist writing from San Dimas, California.
His website is www.askbillsardi.com
Copyright 2001. Distribution or re-publication of this report for
commercial use is forbidden without permission.
CHECKLIST
- Avoid child vaccinations when children are ill
- Insist upon preservative-free vaccines
- Space out the vaccines
- Think of opting out of unnecessary vaccines like the hepatitis vaccine
- Give supplemental vitamin C to children during the vaccination years
- Provide sulfur-rich foods like eggs and asparagus to children
- Provide tryptophan-rich foods to autistic children to improve serotonin levels
- Avoid over-use of antibiotics for young children
- Use acidophilus supplements in between courses of antibiotics
- Pregnant mothers should consume omega-3 fatty acids from flax oil or fish oil to help prolong gestation and prevent premature birth
- Women should be wary of receiving any vaccines during pregnancy
- All children should be provided supplemental omega-3 fatty acids (flax oil) in their feedings since this essential fat has been removed from the food chain
- Zinc, niacin, vitamin A, vitamin E and should probably supplement a child's diet
- Magnesium and vitamin B6 are worthy of a trial among autistic children
- There is no rush to vaccinate children. Request that your doctor provide a list of the entire vaccination schedule he/she has in mind for your children so you can examine it ahead of time.
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